Oh well, I went ahead anyway and here are my results for future reference.
Root cause turned out to be the wiring to the tail door. At some time in the past it had obviously become trapped. The wiring is unwrapped at this point in the loom to provide greater flexibility for the door operation, something of a mistake IMHO. Anyhow, the feed to the heated rear window and the earth were partially severed and had shorted across the rest of the loom, burning out the Central locking wires and toasting the lock ECU module. Oops.
Rewire, bridge duff bits, heatshrink tubing and wrap to sort this. Onto the lock ECU. Unit sourced from FleaBay and my local Opel dealer supplied the codes for the car for the princely sum of 30EUR.
Plugging in OP-COM (or rather a Chinese FleaBay knockoff) produced some odd results in that, while it all worked OK, I had no deadlocks or single-touch 'leccy windows. Going back for a second go I realised that the VIN recorded on the immobiliser side was different to the actual vehicle VIN as recorded in the main ECU. Setting this correctly resulted in some sort of electronic throat clearing. Everything working just fine now.
All in all a fairly simple DIY task, given the correct software to poke the thing after installation.
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