Low profile tyres as used on 19" wheels have very stiff sidewalls that absorb very little of any pot holes that you hit, the run flats as used by BMW are even stiffer and absorb even less. This can cause problems for the wheels and suspension.
Simple solution is to buy a car with 16" or 17" rims. You will have no issues then.
The 19" rims have no advantage other than the bling factor.
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